Women with mild GDM who received dietary intervention, self-monitoring of blood glucose (BG), and insulin therapy had significantly lower risks of macrosomia (5.9% vs 14.3%, P<.001), shoulder dystocia, cesarean delivery (26.9% vs 33.8%, P=.02), and preeclampsia or gestational hypertension (8.6% vs 13.6, P=.01) than those who received standard care in a randomized controlled trial (RCT) of 958 women [11]. The gene discussed is INS; the disease is preeclampsia.