CD274 and small cell lung carcinoma: As shown in Tables 4 and 5, the higher serum concentration of soluble PD-L1 was associated with the higher risk of no response to chemotherapy or SCLC caused death (HR: 1.40, 95% CI: 1.05 ~ 1.87; HR: 1.43, 95% CI: 1.08 ~ 1.87).