PLAT and androgen insensitivity syndrome: The primary aim of the study is to determine the effect of early intensive BP lowering (systolic BP target 140–160 mm Hg) initiated within 6 hours of symptom onset and maintained for 72 hours in AIS patients treated with intravenous tissue plasminogen activator (IV-tPA) on cerebral blood flow (CBF), measured with computed tomographic (CT) perfusion imaging.