Antiphospholipid syndrome (APS) is a disease that manifests clinically as vascular thrombosis (arterial, venous, or small vessel thrombosis) and/or abortion with laboratory results of persistently elevated levels of antiphospholipid antibodies (aPL).[1] Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe complication of patients with APS. This evidence concerns the gene FASLG and chronic thromboembolic pulmonary hypertension.