To address the above hypothesis, our objective was to characterize the metastatic spread of luciferase-expressing MPC cells after intravenous injection in mouse strains featuring different immunologic phenotypes and to compare tumor progression, catecholamine excretion and SSTR2 status of different metastases models with a previously established subcutaneous reference model (NMRI-nude mice) (Ullrich et al. 2014, 2016). Here, SSTR2 is linked to neoplasm.