PRDX1 and breast carcinoma: Hereby, similarly to MCF-7, we observed a significant decrease in the growth rate of ZR-75-1 breast cancer cells harboring the shRNA against PRDX1 (ZR-75-1 shPRDX1), but not PRDX2 (ZR-75-1 shPRDX2), as compared to the controls (ZR-75-1 parental and shNTC) (Fig. 3b).