As an example of a Chr8p-located gene, the TNFRSF10B (tumor necrosis factor receptor superfamily, member 10b, also known as Death Receptor 5) is upregulated (1.95-fold increase) in CRC samples in comparison to normal tissue but its expression decreases in CRC samples bearing a Crh8p loss. Here, TNFRSF10B is linked to colorectal carcinoma.