Interestingly, as reported in Supplementary Table S4, another two genes encoding for eukaryotic translation initiation factors (EIF2S2 and EIF6) are located in Chr20 and are significantly upregulated in comparison to normal tissue (4- and 2-fold change, respectively) and overexpressed comparing cancers bearing Chr20 gain with those with disomic Chr20 (2.2 and 1.67-fold change, respectively). The gene discussed is EIF6; the disease is cancer.