The data showed that POU5F1P4 was over-expressed in several cancer tissues including brain and CNS (central nervous system), colorectal, kidney and other cancers compared to in their normal tissues (Fig. 7a,c; Supplementary Table S15), whereas lower expression was observed in breast and gastric cancer than in their normal tissues (Fig. 7a,b,d; Supplementary Table S15). This evidence concerns the gene POU5F1P4 and cancer.