Even more epidemiologically important, however, is that among the 11 G6PD-deficient positive cases, 7 persons were asymptomatic cases, and only 4 positive cases were with clinical manifestations of the disease, suggesting that the G6PD deficiency played some role in the phenomenon of asymptomatic infection [67]. The gene discussed is G6PD; the disease is hyperinsulinemic hypoglycemia, familial, 4.