In HC-MSC, the TGF-β treatment induced a significant reduction of CD248 mRNA expression levels when compared with UT cells [CD248 mRNA levels in TGF-β HC-MSC 0.07 (0.03–0.15) vs UT HC-MSC 0.96 (0.73–1.17); p < 0.0001], although in SSc-MSC, the levels of CD248 expression were always significantly higher than in HC-MSC. Here, TGFB1 is linked to systemic sclerosis.