Among them, mice lacking Schnurri-2 (Shn2; also called major histocompatibility complex [MHC]-binding protein 2 [MBP-2], or human immunodeficiency virus type I enhancer binding protein 2 [HIVEP2]) have been proposed as a model for schizophrenia and HIVEP2-related intellectual disability with good face and construct validity [4, 7, 8]. The gene discussed is HIVEP2; the disease is Intellectual disability.