ANXA5 and glioblastoma: To determine whether panobinostat and JQ1 commonly induce apoptosis in GBM cells, U87, U251 and serum-free cultured U87 cells were treated with control DMSO, panobinostat, JQ1 or a combination of panobinostat and JQ1 for 48 h, followed by staining with Annexin V and a flow cytometry analysis.