It should also be noted that TRAX and DISC1 share several interacting proteins (e.g., GSK3β and AKAP9; Table 2) and functional pathways/machineries (e.g., the cAMP/PKA pathway, Wnt signaling, intracellular transport and DNA repair; Table 2); thus, they may act together to regulate important pathophysiological events, including the development of mental disorders. The gene discussed is GSK3B; the disease is psychiatric disorder.