McMillin et al. reported a male patient with DA5 in whom a heterozygous mutation c.8153G > C was identified in PIEZO2. This mutation yielded an arginine-to-proline (R2718P) substitution and induced the features of ptosis, ophthalmoplegia, scoliosis, and pulmonary disease [8]. This evidence concerns the gene PIEZO2 and lung disorder.