In this context, after 120 h of interaction, CD14+ monocytes/macrophages showed an alternative phenotype (high expression of CD64 and CD163; Fig. 4a, b) as well as higher levels of PD-L1 than naïve controls (Fig. 4c), which did not have any contact with tumour cells. The gene discussed is FCGR1A; the disease is neoplasm.