More importantly, the DCs pulsed with tumour-specific lysate then matured with full cocktail or IFN-containing cocktail alone, expressed significantly higher levels of the key maturation markers, CD80 (69% or 73%, respectively; p < 0.005), CD86 (78% or 81%, respectively; p < 0.0001), CCR7 (62% or 64%, respectively; p < 0.0001) and CD83 (73% or 75%, respectively; p < 0.0001), compared to the immature DCs (39% vs 5% vs 27% vs 1.7%, respectively) or DCs pulsed with tumour-specific lysate alone (56% vs 15% vs 42% vs 8%, respectively; Fig. 2B). The gene discussed is CCR7; the disease is neoplasm.