The DCs that were matured with an IFN-containing cocktail only or pulsed with tumour-specific lysate and matured with full cocktail, expressed significantly higher levels of CD40 (p < 0.001 or p < 0.005, respectively) and HLA-DR (p < 0.005) compared to immature DC (data not shown). The gene discussed is CD40; the disease is neoplasm.