This interaction results in T‐cell activation and a strong immune response.43 ICAM2 is a glycoprotein that mediates adhesive interactions with T cells and has also been shown to mediate antitumor immune response in human pancreatic carcinogenesis.42 These effects may be caused by telomerization‐associated downregulation of antitumor response genes, which is relevant to the role of telomerization in cancer biology.44 This evidence concerns the gene ICAM2 and cancer.