CD274 and neoplasm: Numerous miRNAs, including miR-15a/miR-16 (73), miR-17-5p (74), miR-93/106b (75), miR-138-5p (76), miR-140/miR-142/miR-340/miR-383 (25), miR-152 (77), miR-155 (78), miR-193 (73), miR-195 (73), miR-324-5p/miR-338 (79) and miR-322/miR-424 (80), have been shown to directly target and inhibit PD-L1 expression in tumor cells.