Since Thr136Ile affects the anxiety‐related personality traits (Lohoff et al. 2008a) and is linked to the anxiety or depressive phenotypes (Vaht et al. 2016), the evolution from Asn to Thr at the 136th site of SLC18A1 might have led to more anxious human minds through positive selection. The gene discussed is SLC18A1; the disease is Anxiety.