This not only permitted the quantitative measurement of IL-17A producing cells in nasal tissue of patients with CRS which showed an increased IL-17A+ live cells in both CRSwNP and CRSsNP from controls but also that CRSwNP exhibited higher IL-17A+ live cells than CRSsNP. The gene discussed is IL17A; the disease is chronic rhinosinusitis without nasal polyps.