NFKB1 and myocardial ischemia: A previous study showed that UA attenuates LPS-induced neuroinflammation via inhibiting the MAPK, Akt, and NF-κB pathways (Xu et al., 2018), and alleviates myocardial ischemia/reperfusion injury via the PI3K/Akt pathway (Tang et al., 2017).