Seventeen articles involving 6,767 patients were included for analysis of clinical presentations of LRRK2-G2385R-related PD; out of these, 5 LRRK2-R1628P–related articles comprising 2,369 patients and 5 LRRK2-R1441G–related articles comprising 1,222 patients were included in the final meta-analysis. This evidence concerns the gene LRRK2 and Parkinson disease.