Our results enable deeper understanding of the underlying genetic characteristics of PD by highlighting G2019S or G2385R variants in LRRK2 as predictors for the development of motor complications, in addition to the well-established factors, such as young age at onset, higher L-dopa dose, and low body weight (Warren Olanow et al., 2013). The gene discussed is LRRK2; the disease is Parkinson disease.