EHMT2 and neoplasm: Drugs that inhibit G9a have been identified and one, diazepin-quinazolin-amine derivative (BIX-01294) shows specificity for G9a over other methyltransferases (Kubicek et al., 2007), is able to modulate H3K9Me2 levels in mammalian cells, induces autophagy in a number of tumour cell lines (Ciechomska et al., 2016), and reduces tumour growth in a mouse model (Ke et al., 2014).