To note, higher levels of α-Actinin-4 or its redistribution in c-kit treated group at day 10 (Fig. 4B) were detected a couple of days after PAN-induced peak of proteinuria, and may precede podocyte cytoskeleton rearrangement in response to change in the microenvironment, and contribute ultimately to proteinuria reduction. Here, KIT is linked to polyarteritis nodosa.