This finding is intriguing given that MLL1, an H3K4 methyltransferase, is essential for neurogenesis [62] and PFC synaptic plasticity [63], is a key regulator of morphogenesis [64] and postmortem human studies and animal models have suggested its involvement in schizophrenia-related cortical dysfunction [65]. Here, KMT2A is linked to schizophrenia.