In the glioma tissues, the gene expression levels of AASDHPPT, NDST2, HS3ST2, CHST3, CHST7, CHST12, CHST15, TPST1, TPST2, PAPSS1 and PAPSS2 were significantly up-regulated (p < 0.05, Fig. 4). This evidence concerns the gene PAPSS1 and central nervous system cancer.