We counted the number of GAP43-positive neurons in the hippocampus (n = 6 mice, 12 brain sections) and found that there was an increase in the number of GAP43-positive hippocampal neurons in mini-GAGR–treated 3xTg-AD mice compared with vehicle-treated (mean ± S.E.): 12.25 ± 3.76 for control CA1-CA2 versus 27.58 ± 3.53 for mini-GAGR CA1-CA2, p = 0.007; 57.83 ± 7.64 for control CA3 versus 76.92 ± 5.28 for mini-GAGR CA3, p = 0.052. Here, GAP43 is linked to Alzheimer disease.