NFE2L2 and Alzheimer disease: We measured the intensities of the CA1–CA3 and DG regions and counted the number of p-Nrf2–positive neurons in the regions using Metamorph software for the calculation of average intensity ± S.E. and average number ± S.E. The intensity of p-Nrf2 was higher in the CA1–CA3 and DG regions of mini-GAGR–treated 3xTg-AD mice compared with vehicle-treated 3xTg-AD mice (-fold changes: CA1–CA3, 1.17 ± 0.08 for control versus 1.46 ± 0.12 for mini-GAGR (p = 0.0594); DG, 1.01 ± 0.05 for control versus 1.26 ± 0.07 for mini-GAGR (p < 0.01)) (Fig. 9I).