Apo J has been reported to be closely related to cardiovascular diseases, such asatherosclerosis and restenosis after angioplasty.14,15 Ishikawa et al.7 revealed the distribution of Apo J in the extracellular matrixof endarterium in human atherosclerotic aorta, and its potential protective roleagainst human atherosclerosis by cholesterol transport from the aortic wall to theliver. The gene discussed is CLU; the disease is cardiovascular disorder.