The four genes which had multiple undercovered cohorts were the long non-coding RNAs (lncRNAs) MALAT1 and XIST and the protein-coding genes SETD1B and SOX11. The undercovered cohorts of the three protein coding genes had strong similarities, with PRAD tumors in particular uniformly showing insufficient coverage at all three gene loci (Fig 1 and B in S2 Fig). This evidence concerns the gene XIST and prostate adenocarcinoma.