Chevrier et al. (51) quantitatively and positively correlated Ki-67 expression based on the H-score and tumor grade given by the Gleason score: H-score 2, 21, and 52 for Gleason score (3 + 3 = 6, 3 + 4 = 7, and 4 + 4 = 8), respectively (p = 0.0002). The gene discussed is MKI67; the disease is neoplasm.