Deletion of capns1 in the mammary epithelium correlated with a significant delay in spontaneous tumor onset (median time KO = 318 vs WT = 300 days; p = 0.0277); and 10% of KO mice remained tumor-free beyond 600 days of age while nearly all WT mice had developed tumors by this age (Figure 1). This evidence concerns the gene CAPNS1 and neoplasm.