In the 15 types of cancer, only cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) samples showed significantly poorer OS in the samples with higher HMCN1 VAFs (n = 7, VAF ≥ 0.30) than those with lower VAFs (n = 15, VAF < 0.30) (log-rank test: P = 0.048) (Supplementary Figure 7). The gene discussed is HMCN1; the disease is cancer.