Isolated from prostate tumor and associated cells, for example, Calcinotto and colleagues identified two IL-23-regulated proteins (STAT3 and RORγ) that support androgen-receptor-associated tumor growth [14] in myeloid-derived suppressor cells (MDSCs) (including monocytes and neutrophils) at an immature state [15]. This evidence concerns the gene STAT3 and prostate neoplasm.