In this picture, with the idea to: (1) identify the pathogenic players in PsA, (2) discriminate the immunological pathways that are in common or are distinct between psoriasis and PsA, and (3) identify new disease activity markers for PsA, we have investigated the presence of LL37 and related autoantibodies in PsA and psoriasis patients and analyzed their correlations with clinical parameters and inflammatory factors. The gene discussed is CAMP; the disease is psoriasis.