GPT and acute myeloid leukemia: We found that the levels of ALT, AST, and LDH in the culture supernatant of AML-12 cells increased as the CoCl2 stimulation time increased (Fig. 6A) and the levels of ALT, AST, and LDH in the supernatants of cells treated with HBSP were lower than those without HBSP treatment (Fig. 6B).