G6PD and cholelithiasis: In humans, in addition to the role of G6PD in preventing hemolysis (erythrocyte lysis), the anti-oxidant property of G6PD may relate to development of a variety of other pathologies, including kidney injury, heart failure, psychiatric disorder, diabetes, cholelithiasis, and cataract44–52, suggesting that G6PD deficiency can be an underestimated risk factor for multiple human pathologies.