In the AD cohort, unsurprisingly, ApoE genotypes 3/4 and 4/4 were significantly enriched (p = 3.0 × 10−4 and p = 0.001, χ2 test, respectively); for FTD patients, the ApoE genotype 4/4 was also significantly enriched (p = 6.7 × 10−4, χ2 test). This evidence concerns the gene APOE and Alzheimer disease.