EZHIP and ependymoma: H3K27M mutations were observed in 4.2% of PF-EPN-A tumors and occurred only in the type 1 subgroup; CXorf67 mutations were observed in 9.4% of PF-EPN-A ependymomas, but not in other types; high levels of WT or mutant CXorf67 were observed in all PF-EPN-A subtypes, except the 1f subtype, which was enriched for H3K27 mutations [231].