NFKB1 and glioblastoma: Thus, Teng et al. have explored the properties of glioblastoma-derived neurospheres, showing that these cells undergo a differentiation process when grown in the presence of serum; however, under these conditions, a small proportion remained as floating, undifferentiated cells: interestingly, these floating cells displayed enhanced cancer stem cell properties, associated with a molecular and phenotypic signature, including also a resistance to chemo/radiation therapies, a pronounced tumor-forming capacity and NFkB activation [350].