KDM6A and medulloblastoma: Importantly, mutations in six other KDM members (observed less frequently that KDM6A mutations), including KDM1A, KDM3A, KDM4A, KDM5A, KDM5B, and KDM7A were detected exclusively in Groups 3 and 4 medulloblastomas, thus supporting the concept of a broad disruption of lysine demethylation in these tumors [168].