ITGB1 and hepatocellular carcinoma: However, treatment with StemoleculeTM ROCK I Inhibitor (10 nM, CAS# 203911-26-6, Stemgent Inc.)for 12 h significantly reduced the enhancing effects of linc-ITGB1 overexpression on proliferation (Figure 4A), migration (Figure 4B), and invasion (Figure 4C) of HCC cells (P<0.05).