A prospective study included 859 patients revealed that preoperative FGF23 level was independently predictor of postoperative AKI in the context of elective cardiac surgery [25], and other study in 19 children discovered that relative risk of developing AKI was 2.0 when preoperative FGF23 level was >86 RU/mL (p = .033) [26]. This evidence concerns the gene FGF23 and acute kidney injury.