ARC and cardiac hypertrophy: In a qPCR screening of 100 randomly selected circRNAs, mm9‐circ‐012559, renamed HRCR, was found to be decreased in a mouse model of heart hypertrophy.68 CircRNA HRCR can act as a sponge for miR‐233, resulting in the increase in the miR‐233‐target ARC and reducing cardiac hypertrophy and heart failure in mice.