ART4 and colorectal carcinoma: ND‐1 is a mAb which was produced by hybridoma technology using the CRC CL187 cells as the immunogen.15 Previous researches showed that LEA was a glycoprotein mainly expressed on CRC cell membrane.15 IHC primarily revealed that LEA expression was associated with T stage of CRC.16 Notably, LEA was detectable in the serum and ascites of CRC patients, leading to a convenient clinical access.15 Accumulating data suggested that LEA might serve as a valuable diagnostic marker for CRC, but its molecular features remained unknown.