Despite the enrichment of BRN2 expression in melanoma cells, and the established link of BRN2 to the regulation of MITF expression (Goodall et al., 2008; Wellbrock et al., 2008), the correlation of BRN2 and MITF mRNA levels was not significant in all data sets (Figure 1b and Supporting Information Figure S1B). The gene discussed is POU3F2; the disease is melanoma.