Using RNAi we confirmed previous findings (Cook et al., 2005; Simmons et al., 2017; Smith et al., 2016; Thurber et al., 2011; Wellbrock et al., 2008) that both, BRN2 and PAX3 contribute to MITF expression in melanoma cells (Figure 3a and b and Supporting Information Figure S3). This evidence concerns the gene POU3F2 and melanoma.