Specifically, Survivin has previously been suggested as a sensitivity marker based on cell line models (Rodel et al. 2003) and FGFR-dependent signaling plays a central role due to its physiological functions (Turner and Grose 2010; Heinzle et al. 2011), especially in CRC (Sonvilla et al. 2008, 2010; Koneczny et al. 2015; Erdem et al. 2017). Here, BIRC5 is linked to colorectal carcinoma.