Upon stimulation by LPS for 24 h, the percentage of CD86+ cells as well as the CD86 mRNA and IL-12 mRNA levels was significantly decreased in THP-1 cell-derived macrophages treated with eutopic or ectopic endometrial homogenate from endometriosis patients, as compared with levels in those treated with normal endometrial homogenates (Figure 2). This evidence concerns the gene CD86 and endometriosis.