In certain types of tumors, EpCAM is associated with advance stage disease and overall survival.5 The association of EpCAM with proliferation, adhesiveness, tissue stabilization, promotion of tumor growth, and metastasis suggests that EpCAM is a pleiotropic molecule that potentially offers therapeutic applications in cancer treatment.6 Generally, the expression of EpCAM is restricted to epithelia. The gene discussed is EPCAM; the disease is neoplasm.