Dangi-Garimella et al. revealed that pre-miR-let-7a induced the Dicer-processed mature let-7a and subsided HMGA2 and Snail and, therefore, decreased invasion of breast cancer cells.35 In our survey, let-7a transcript level was augmented after Snail-1-specific siRNA knockdown. This evidence concerns the gene HMGA2 and breast cancer.