KIAA1524 (also known as CIP2A) inhibits protein phosphatase 2A tumor suppressor activity in human neoplastic diseases by favoring the sustained activation of Ras and cellular myelocytomatosis viral oncogene (c-myc).111 Its participation in the signalosome of PD-L1 would explain the pro-carcinogenic activities associated with PD-L1 overexpression. Here, CD274 is linked to neoplasm.