However, compared to controls, protein expression for HSL and ATGL as well as for phosphorylated HSL p660-HSL and p565-HSL was significantly reduced upon HF and HF/n-3 (Fig. 4b, c), whereas p563-HSL was only significantly lower for HF/n-3 but not for HF. The gene discussed is PNPLA2; the disease is hydrops fetalis.