Eventual confounding factors possibly explaining overweight were found in five of 28 overweight cases: two patients had a diagnosis of type I diabetes in childhood and were insulin dependent and three patients had a diagnosis of autoimmune thyroiditis during CD diagnosis work-up and they still were not on levothyroxine treatment at the first CD visit time, perhaps explaining their weight increase due to an initial hypothyroidism. Here, INS is linked to autoimmune thyroid disease.